In the stiletto on pill

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Use at the pill of profess to convinced and capsule, its structure is increasingly complex, this makes pharmacy business can produce more and useful medicaments in order to serve the public. Laser hit mark and small processing technique to act important role on the production of a few medicaments. Newest medicaments releases the pill with complex system and capsule (a general designation: Medicaments releases a system) have huge advantage, for instance it can dominate the release time of medicaments well and truly, make people OK use this reason at water-solubility low, cannot the medicaments of profess to convinced. An example is " accuse commentate pump " , it was to use remedy layer and " extruding layer " , two by inclose of half fully filmy bag. Medicaments enters system inside hind, water element is passed show film partly, make extruding layer expands. This makes the alveolus that medicaments passes film to go up in medicaments layer is released by fixed rate (1 seeing a picture) . Graph 1 , accuse commentate the pill structure of pump included layer of a medicaments and an extruding layer, two by inclose of half the bag that show film. Accuse commentate the typical cost of dimension of the alveolus in pump arrives in 600m about between 1 Mm. In light of the standard that makes treatment according to other nicety, the tolerance of alveolus diameter and appearance normally not quite accurate. Normally tolerance has the alveolus that demarcate diameter is 600m ± 100m, ovality is 1.

0 to 1.

5. The alveolus that has such dimension and tolerance can use simple mechanical method to obtain. Nevertheless, use machining means unavailable enough productivity and platform of other pharmacy treatment close suitably. Contrary, the treatment rate that pill laser stiletto can get is 100 thousand / hour, and the alveolus that uses this technology to get dimension tolerance and exterior all accord with a requirement very easily. Its main function forms system of stiletto of pill of laser of treatment process overview the component is made by company of American Control Micro Systems, this company (network address Www.

Cmslaser.

Com) be located in Florida city Winter Park. If the graph is shown 2 times, this special construction adopted platform of two laser stiletto, can undertake to pill bosseyed, double-faced perhaps stiletto. Power is used to to the pulse CO2 laser of 500W in 100W undertake machining, because of its output wavelengh is in 10.

6m, all and organic thing that can be used at medicaments almost is absorbed. And a lot of organic matter are to be not absorbed 1.

Of 06 M laser. These organic matter still can absorb ultraviolet light well, but ultraviolet the productivity that laser cannot offer enough power to need in order to get place. In this application, laser of use pulse type is more appropriate, because it can output higher peak value power, peak value power is high make treatment rate rapidder, the laser of pulse still can be reduced by the negative effect that adds tropics to come, become angry like material or arise drossily. Graph 2, system of typical laser pill stiletto included different component. Above all, pill enters glassware through a disk type each is sent conveyer belt to be discharged. Accuse commentate the extruding layer of pump pill and medicaments layer normally color is different, because need stiletto, is medicaments layer. Pill decides through detector of a color its face towards. Subsequently, another condition detector decides whether pill is passed, if color detector shows tablet day to go up, so spark the operation of laser stiletto. Subsequently, pill passes system of observation of a mechanical. The pill that this system adopts to every takes next digital pictures, and with its 4 pieces of his possible result appearances are compared. Among them two pieces of delegates are OK " pass " , two pieces express must " refuse " . Unqualified pill is blown by a system that drives by gas from conveyer belt. Because the tradition contains fixed rate, and the system that blow air has proper delay time, judge a product when observation system so unqualified, "Refuse " mode is started instantly. This process is met normally arrive before unqualified pill two pill are blown together. Reject mode to be able to leave all the time normally, observe continuously till the system 5 eligible pill, that is to say, they satisfy two " eligible " the any in the standard. Another condition detector (graph 2 in did not show) frame after boasting air system, be in with ensuring " refuse " it is OK to there is pill when mode is started through. In so strict filtration the condition falls, although some good pill also are blown off, but the system still carries the manufacturing efficiency of 98% (namely pill percent of pass) . After Nextpage adopts platform of stiletto of the first laser, all pill are turned over another, send stiletto of the 2nd laser platform as conveyer belt. The treatment means of the 2nd platform and before one exactly like. When first time stiletto, the surface on some pill is not medicaments layer, the action of the 2nd platform undertakes stiletto to these pill namely. In the other one aspect of the matter of automation line, has machined pill is sent collect a bucket, preparation undertakes coating is mixed finally print. The output rate that to make the system gets achieves flight stiletto horary 100 thousand pill, be necessary to allow a system can " flight " type stiletto, that is to say, can not have stand, the circumstance that perhaps decelerates the product on conveyer belt to carry rate happens. To laser stiletto process, can two kinds of methods realize this treatment process. The first, when pill obtains booked position as conveyer belt, use odd pulse to come only to every pill stiletto. The odd pulse here must have enough peak value power the whole case with purify pill, pulse must very short, so that won't make pill mobile in stiletto process; What what get otherwise is a slit, is not an alveolus. The 2nd kind of method is to use much pulse. When using this method, must undertake to the shift of the pill on conveyer belt optics is tracked, such doing what can make sure every pulse is hit to pill is same dot. Normally, this process You Zhenjing (galvanometric with scanning illuminator) come true jointly with scanning lens (see a picture 3) . The structural characteristic of this scanning lens makes the Jiao Ban that it can maintain appropriate, although the distance between lens and pill as the shift of pill have change a bit, jiao Ban also can keep changeless. The conveyer belt that uses here can prevent pill to slide on conveyer belt. The design with encode feedback technology and unique conveyer belt makes what every pulse can hit well and truly to pill same dot. Although much pulse technology makes deferent system more complex, but when using this technology, the 1/5 that laser power issues for odd pulse circumstance only comes 1/4. Use power is lower mean systematic cost low, the expenditure that because offsetted very easily in cost of reductive of the place on laser,become complex as a result of the system and brings. Use place to need pulse the maximum of several is mix by the visual field of lens of the speed of conveyer belt, scanning the repetition of laser frequency decides. A system of typical laser pill stiletto uses nine pulse to hit an alveolus. Graph 3, flight stiletto technology used Zhen Jing (included galvanometric with scanning illuminator) with scanning lens, such pill reach also won't interrupt the process of stiletto. Laser has strict pulse modulation parameter is very important for the cost to stiletto and efficiency. Normally, quadrate pulse is better than triangular pulse, because former deliver in the energy of odd pulse more effective, that is to say, to same for treatment process, requires pulse amount is fewer. Wants pulse number is reduced mean treatment the window is wider, treatment procedure is more quick. In addition, because reduced energy waste, the to material destruction that because heat,causes is smaller also. Company of Control Micro Systems used batten of series of K of Coherent company diamond in a lot of pill stiletto systems that its make discharge CO2 laser. Besides have modulation of quadrate wave pulse beyond, diamond K series still has the advantage of a few respects to conduce to flight stiletto. In these advantages, one the may most important is these laser can be offerred " need power namely " . What it points to is the system can control parameter of laser pulse modulation in real time, be in even fall when necessary odd pulse. Compare with this photograph, making the pulse of laser of multitask course of study repeat frequency is fixed, adjustable perhaps humorous range is very narrow. In addition, in a lot of other laser types, measuring individual pulse only is no good, because laser needs,the ability after a few pulse can reach steady state. And the design means of attrib wattle discharge does not have this problem, it can produce steady pulse instantly. Such, "Need power namely " very useful, because it can be in real time aleatoric bulk is provided in product line (it is alterable even) input. As rigid as what adjust deferent system structure so that pill is OK with fixed repeat frequency laser synchronism to be compared, offer " need power namely " handy much. Anyhow, the field uses in pharmacy line of business, yield is high and the stability that machines a process is crucial. The fact proves, the output of laser of CO2 of attrib wattle discharge can satisfy these two requirements. The laser system with these mature technologies can provide very reliable performance, running stores cost is low. These advantages to pill manufacturer it is all in all, because they are faced with policy to go up and the pressure on the market, must reduce totle drilling cost so. Article author Frank Gaebler assumes office at Coherent company, his email is: Frank.

Gaebler@coherent.

Com, firm network address: Www.

Coherent.

Com. CNC Milling